Browse active challenges from the government
Understand what challenges and prize competitions from the federal government are active now. Explore key information, like important dates and prizes. Learn how you can apply.
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2025 “$100,000 Start an SUD Startup" Challenge
Test your research idea about drug use, misuse, and substance abuse disorder (SUD).
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2026 NASA Revolutionary Aerospace Systems Concepts – Academic Linkage (RASC-AL) Competition
Develop new ideas and prototypes that could help people explore and work on the Moon, Mars, and beyond. Apply now.
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Beauty + Health: Youth Graphic Medicine Challenge
Develop comics to help reduce health risks and pressure to meet society’s beauty standards.
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Gateway to Blue Skies 2026 Competition
Design new ways to improve aircraft maintenance, and make aviation safer, more efficient, or more affordable.
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NASA’s 2026 Human Lander Challenge
Help shape the future of human spaceflight. U.S.-based college students: learn more and apply.
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NIH Complement Animal Research in Experimentation NAMs Reduction to Practice Challenge
Develop human-based non-animal methods (NAMs) – including lab-based human cell systems, computer models, and biochemical assays.
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Oligonucleotide Toxicity (OligoTx) Open Data Challenge
Help improve in silico models for predicting toxicity using high-quality, open datasets.
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Presidential 1776 Award
High school students: showcase your understanding of civics and knowledge of America’s founding.
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Tactical Missile Innovation Challenge
Propose a new way to develop more affordable and adaptable all-up-round (AUR) missiles.
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Targeted Genome Editor Delivery (TARGETED) Challenge
Develop programmable delivery systems and non-viral delivery across the blood-brain barrier.
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