Oligonucleotide Toxicity (OligoTx) Open Data Challenge

Help improve in silico models for predicting toxicity using high-quality, open datasets.

Apply to create high-quality, open datasets using human in vitro systems to help predict toxicity from oligonucleotide therapies and that can lead to development of improved in silico models for predicting toxicity of an oligo. NCATS is especially interested in datasets that support models for liver, kidney, immune, blood, or chronic nervous system toxicity. 

Key information
Sponsoring agencyNational Institutes of Health
Start date10/19/2025 11:59 ET
End date2/28/2026 11:59 ET
Challenge typeScientific
PrizesTotal cash prizes: $500,000
Contact 

Apply for the Oligonucleotide Toxicity (OligoTox) Open Data Challenge

LAST UPDATED: February 5, 2026

SHARE THIS PAGE:

Have a question?

Ask a real person any government-related question for free. They will get you the answer or let you know where to find it.

Top